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Upstream bio, inc.UPB.US Overview

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UPB Recent Performance

-0.04%

Upstream bio, inc.

0.05%

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-0.31%

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UPB Key Information

UPB Financial Forecast

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QuarterlyEPS ForecastQoQMaxMin
2026Q1
2026Q2
2026Q3
2026Q4
2027Q1

UPB Profile

Upstream Bio, Inc., a clinical-stage biotechnology company, develops treatments for inflammatory diseases that focuses on severe respiratory disorders. It develops verekitug, a monoclonal antibody that targets and inhibits the thymic stromal lymphopoietin receptor. The company also develops therapies to treat severe asthma, chronic rhinosinusitis with nasal polyps, and chronic obstructive pulmonary disease. Upstream Bio, Inc. was incorporated in 2021 and is based in Waltham, Massachusetts.

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UPB FAQ

This disclaimer is provided by TradingValley Inc. and includes any messages, news, research, analysis, prices or other information provided by the Company's website, the application "Growin App" and other services provided through the Company's website. It is only general market information for educational and investment decision-making reference, and does not constitute any investment advice. View Growin Disclaimer

UPB Earnings Table

Unit : USD

QTRNon-GAAP EPSEPS YoYEPS Surprise %SalesSales YoYSales Surprise %NPM
Current
2025Q4
2025Q3
2025Q2
2025Q1
METRIC
VALUE
vs. INDUSTRY
EPS (TTM)
-1.36
PE Ratio (TTM)
-
Forward PE
-
PS Ratio (TTM)
148.27
PB Ratio
1.10
Price-to-FCF
-
METRIC
VALUE
vs. INDUSTRY
Gross Margin
100.00%
Net Margin
-4550.25%
Revenue Growth (YoY)
37.40%
Profit Growth (YoY)
37.40%
3-Year Revenue Growth
14.92%
3-Year Profit Growth
14.92%
METRIC
VALUE
vs. INDUSTRY
EPS (TTM)
-1.36
PE Ratio (TTM)
-
Forward PE
-
PS Ratio (TTM)
148.27
PB Ratio
1.10
Price-to-FCF
-
Gross Margin
100.00%
Net Margin
-4550.25%
Revenue Growth (YoY)
37.40%
Profit Growth (YoY)
37.40%
3-Year Revenue Growth
14.92%
3-Year Profit Growth
14.92%
  • When is UPB's latest earnings report released?

    The most recent financial report for Upstream bio, inc. (UPB) covers the period of 2025Q3 and was published on 2025/09/30. This report is prepared according to IFRS/US GAAP standards and includes key financial indicators—Revenue, Profitability, Cash Flow, and Capital Structure. This information is essential for investors evaluating UPB's short-term business performance and financial health. For the latest updates on UPB's earnings releases, visit this page regularly.

  • What is the operating profit of UPB?

    According to the latest financial report, Upstream bio, inc. (UPB) reported an Operating Profit of -37.83M with an Operating Margin of -5,539.39% this period, representing a decline of 100.25% compared to the same period last year. Operating Profit reflects the company's core business efficiency and cost control, making it a key indicator for evaluating operational strength and profitability.

  • How is UPB's revenue growth?

    In the latest financial report, Upstream bio, inc. (UPB) announced revenue of 683K, with a Year-Over-Year growth rate of 12.52%. Revenue growth can be driven by product mix changes, market share expansion, price adjustments, or international market penetration. Investors should also monitor gross margin and regional revenue distribution for a comprehensive view of growth quality and sustainability.

  • How much debt does UPB have?

    As of the end of the reporting period, Upstream bio, inc. (UPB) had total debt of 1.42M, with a debt ratio of 0. Short-term debt comprises a higher/lower proportion. The level of financial leverage directly impacts the company's capital structure and interest coverage. If debt is high, pay attention to interest expenses and refinancing risks. Conversely, a low-leverage structure indicates greater risk tolerance but potentially less growth flexibility.

  • How much cash does UPB have?

    At the end of the period, Upstream bio, inc. (UPB) held Total Cash and Cash Equivalents of 72.36M, accounting for 0.18 of total assets. Both current and quick ratios indicate robust short-term debt repayment ability. High cash reserves typically mean the company has strong liquidity, supporting operational needs, expansion investments, or shareholder returns.

  • Does UPB go with three margins increasing?

    In the latest report, Upstream bio, inc. (UPB) did not achieve the “three margins increasing” benchmark, with a gross margin of 100%%, operating margin of -5,539.39%%, and net margin of -4,941.1%%. This demonstrates limited improvement in profitability, which is a key signal for fundamental analysis. Investors should consider margin trends alongside other financial indicators to assess UPB's profit trajectory and future growth potential.

  • Is UPB's EPS continuing to grow?

    According to the past four quarterly reports, Upstream bio, inc. (UPB)'s earnings per share (EPS) shows a steady growth trend, with the latest EPS at -0.63. If EPS continues to rise due to revenue growth and cost optimization, it can support P/E valuation recovery and attract long-term investors.

  • What is the FCF of UPB?

    Upstream bio, inc. (UPB)'s Free Cash Flow (FCF) for the period is -22.3M, calculated as Operating Cash Flow minus Capital Expenditures, representing a fall of 56.1% compared with the previous period. Positive FCF growth provides stable funding for dividends, debt repayment, or strategic acquisitions, and is an important measure of true profitability and shareholder return potential.