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-4.92%
Syndax pharmaceuticals, inc.
-3.61%
Avg of Sector
-2.16%
S&P500

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| Quarterly | EPS Forecast | QoQ | Max | Min |
|---|---|---|---|---|
| 2026Q1 | ||||
| 2026Q2 | ||||
| 2026Q3 | ||||
| 2026Q4 | ||||
| 2027Q1 |
Syndax Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, develops therapies for the treatment of cancer. Its lead product candidates are SNDX-5613, which is in phase 1/2 clinical trial targeting the binding interaction of Menin with the mixed lineage leukemia 1 protein for the treatment of MLL-rearranged (MLLr) and nucleophosmin 1 mutant acute myeloid leukemia (NPM1c AML); and SNDX-6352 or axatilimab, a monoclonal antibody that blocks the colony stimulating factor 1, or CSF-1 receptor for the treatment of patients with chronic graft versus host disease (cGVHD). The company is also developing Entinostat. It also has collaborative research and development agreement with National Cancer Institute; a clinical trial agreement with Eastern Cooperative Oncology Group; and a license agreement with Kyowa Hakko Kirin Co., Ltd. Syndax Pharmaceuticals, Inc. was incorporated in 2005 and is headquartered in Waltham, Massachusetts.Massachusetts.
Unit : USD
| QTR | Non-GAAP EPS | EPS YoY | EPS Surprise % | Sales | Sales YoY | Sales Surprise % | NPM |
|---|---|---|---|---|---|---|---|
| Current | |||||||
| 2025Q4 | |||||||
| 2025Q3 | |||||||
| 2025Q2 | |||||||
| 2025Q1 |
The most recent financial report for Syndax pharmaceuticals, inc. (SNDX) covers the period of 2025Q4 and was published on 2025/12/31. This report is prepared according to IFRS/US GAAP standards and includes key financial indicators—Revenue, Profitability, Cash Flow, and Capital Structure. This information is essential for investors evaluating SNDX's short-term business performance and financial health. For the latest updates on SNDX's earnings releases, visit this page regularly.
According to the latest financial report, Syndax pharmaceuticals, inc. (SNDX) reported an Operating Profit of -62.55M with an Operating Margin of -91.01% this period, representing a growth of 35.09% compared to the same period last year. Operating Profit reflects the company's core business efficiency and cost control, making it a key indicator for evaluating operational strength and profitability.
In the latest financial report, Syndax pharmaceuticals, inc. (SNDX) announced revenue of 68.73M, with a Year-Over-Year growth rate of 794.9%. Revenue growth can be driven by product mix changes, market share expansion, price adjustments, or international market penetration. Investors should also monitor gross margin and regional revenue distribution for a comprehensive view of growth quality and sustainability.
As of the end of the reporting period, Syndax pharmaceuticals, inc. (SNDX) had total debt of 345.43M, with a debt ratio of 0.65. Long-term debt comprises a higher/lower proportion. The level of financial leverage directly impacts the company's capital structure and interest coverage. If debt is high, pay attention to interest expenses and refinancing risks. Conversely, a low-leverage structure indicates greater risk tolerance but potentially less growth flexibility.
At the end of the period, Syndax pharmaceuticals, inc. (SNDX) held Total Cash and Cash Equivalents of 135.03M, accounting for 0.25 of total assets. Both current and quick ratios indicate robust short-term debt repayment ability. High cash reserves typically mean the company has strong liquidity, supporting operational needs, expansion investments, or shareholder returns.
In the latest report, Syndax pharmaceuticals, inc. (SNDX) did not achieve the “three margins increasing” benchmark, with a gross margin of 96.1%%, operating margin of -91.01%%, and net margin of -99%%. This demonstrates limited improvement in profitability, which is a key signal for fundamental analysis. Investors should consider margin trends alongside other financial indicators to assess SNDX's profit trajectory and future growth potential.
According to the past four quarterly reports, Syndax pharmaceuticals, inc. (SNDX)'s earnings per share (EPS) shows a steady growth trend, with the latest EPS at -0.78. If EPS continues to rise due to revenue growth and cost optimization, it can support P/E valuation recovery and attract long-term investors.
Syndax pharmaceuticals, inc. (SNDX)'s Free Cash Flow (FCF) for the period is -69.54M, calculated as Operating Cash Flow minus Capital Expenditures, representing a fall of 21.18% compared with the previous period. Positive FCF growth provides stable funding for dividends, debt repayment, or strategic acquisitions, and is an important measure of true profitability and shareholder return potential.
The latest valuation data shows Syndax pharmaceuticals, inc. (SNDX) has a Price-To-Earnings (PE) ratio of -6.39 and a Price/Earnings-To-Growth (PEG) ratio of -0.59. A PEG below 1 usually suggests the market is underestimating growth potential, while a PEG above 1 indicates high growth expectations are already priced in. Investors should conduct a comprehensive valuation by considering historical growth, market forecasts, and industry cycles.