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Protagonist therapeutics, inc.PTGX.US Overview

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PTGX Recent Performance

1.21%

Protagonist therapeutics, inc.

0.05%

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-0.31%

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PTGX Financial Forecast

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QuarterlyEPS ForecastQoQMaxMin
2026Q1
2026Q2
2026Q3
2026Q4
2027Q1

PTGX Profile

Protagonist Therapeutics, Inc., a biopharmaceutical company, discovers and develops peptide-based therapeutic drugs to address hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing rusfertide (PTG-300), an injectable hepcidin mimetic that is in Phase II clinical trials for the treatment of patients with polycythemia vera and hereditary hemochromatosis, as well as for the treatment of other blood disorders; PN-943, an oral, alpha-4-beta-7 integrin- specific antagonist peptide that is in Phase II clinical trials for treating inflammatory bowel disease (IBD); and PN-235, an orally delivered interleukin-23 receptor specific antagonist for the treatment of IBD and non-IBD indications. The company has a license and collaboration agreement with Janssen Biotech, Inc. Protagonist Therapeutics, Inc. was incorporated in 2006 and is headquartered in Newark, California.

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PTGX FAQ

This disclaimer is provided by TradingValley Inc. and includes any messages, news, research, analysis, prices or other information provided by the Company's website, the application "Growin App" and other services provided through the Company's website. It is only general market information for educational and investment decision-making reference, and does not constitute any investment advice. View Growin Disclaimer

PTGX Earnings Table

Unit : USD

QTRNon-GAAP EPSEPS YoYEPS Surprise %SalesSales YoYSales Surprise %NPM
Current
2025Q4
2025Q3
2025Q2
2025Q1
METRIC
VALUE
vs. INDUSTRY
EPS (TTM)
-2.08
PE Ratio (TTM)
139.52
Forward PE
-
PS Ratio (TTM)
125.10
PB Ratio
8.93
Price-to-FCF
105.05
METRIC
VALUE
vs. INDUSTRY
Gross Margin
100.00%
Net Margin
-282.83%
Revenue Growth (YoY)
-89.41%
Profit Growth (YoY)
-89.41%
3-Year Revenue Growth
-100.00%
3-Year Profit Growth
-100.00%
METRIC
VALUE
vs. INDUSTRY
EPS (TTM)
-2.08
PE Ratio (TTM)
139.52
Forward PE
-
PS Ratio (TTM)
125.10
PB Ratio
8.93
Price-to-FCF
105.05
Gross Margin
100.00%
Net Margin
-282.83%
Revenue Growth (YoY)
-89.41%
Profit Growth (YoY)
-89.41%
3-Year Revenue Growth
-100.00%
3-Year Profit Growth
-100.00%
  • When is PTGX's latest earnings report released?

    The most recent financial report for Protagonist therapeutics, inc. (PTGX) covers the period of 2025Q4 and was published on 2025/12/31. This report is prepared according to IFRS/US GAAP standards and includes key financial indicators—Revenue, Profitability, Cash Flow, and Capital Structure. This information is essential for investors evaluating PTGX's short-term business performance and financial health. For the latest updates on PTGX's earnings releases, visit this page regularly.

  • Where does PTGX fall in the P/E River chart?

    According to historical valuation range analysis, Protagonist therapeutics, inc. (PTGX)'s current price-to-earnings (P/E) ratio is -42.7, placing it in the Overvalued zone on the P/E River chart. This level indicates that the market's expectations for future earnings are already reflected in the share price, with the valuation currently leaning optimistic. Investors are advised to further examine the company's fundamentals and its position in the industry cycle to validate whether the valuation is justified.

  • What is the operating profit of PTGX?

    According to the latest financial report, Protagonist therapeutics, inc. (PTGX) reported an Operating Profit of -50.36M with an Operating Margin of -677.09% this period, representing a decline of 139.72% compared to the same period last year. Operating Profit reflects the company's core business efficiency and cost control, making it a key indicator for evaluating operational strength and profitability.

  • How is PTGX's revenue growth?

    In the latest financial report, Protagonist therapeutics, inc. (PTGX) announced revenue of 7.44M, with a Year-Over-Year growth rate of -95.64%. Revenue growth can be driven by product mix changes, market share expansion, price adjustments, or international market penetration. Investors should also monitor gross margin and regional revenue distribution for a comprehensive view of growth quality and sustainability.

  • How much debt does PTGX have?

    As of the end of the reporting period, Protagonist therapeutics, inc. (PTGX) had total debt of 10.32M, with a debt ratio of 0.02. Long-term debt comprises a higher/lower proportion. The level of financial leverage directly impacts the company's capital structure and interest coverage. If debt is high, pay attention to interest expenses and refinancing risks. Conversely, a low-leverage structure indicates greater risk tolerance but potentially less growth flexibility.

  • How much cash does PTGX have?

    At the end of the period, Protagonist therapeutics, inc. (PTGX) held Total Cash and Cash Equivalents of 128.39M, accounting for 0.19 of total assets. Both current and quick ratios indicate robust short-term debt repayment ability. High cash reserves typically mean the company has strong liquidity, supporting operational needs, expansion investments, or shareholder returns.

  • Does PTGX go with three margins increasing?

    In the latest report, Protagonist therapeutics, inc. (PTGX) did not achieve the “three margins increasing” benchmark, with a gross margin of 100%%, operating margin of -677.09%%, and net margin of -596.8%%. This demonstrates limited improvement in profitability, which is a key signal for fundamental analysis. Investors should consider margin trends alongside other financial indicators to assess PTGX's profit trajectory and future growth potential.

  • Is PTGX's EPS continuing to grow?

    According to the past four quarterly reports, Protagonist therapeutics, inc. (PTGX)'s earnings per share (EPS) shows a declining trend, with the latest EPS at -0.7. If EPS continues to rise due to revenue growth and cost optimization, it can support P/E valuation recovery and attract long-term investors.

  • What is the FCF of PTGX?

    Protagonist therapeutics, inc. (PTGX)'s Free Cash Flow (FCF) for the period is -37.12M, calculated as Operating Cash Flow minus Capital Expenditures, representing a fall of 25.88% compared with the previous period. Positive FCF growth provides stable funding for dividends, debt repayment, or strategic acquisitions, and is an important measure of true profitability and shareholder return potential.

  • What are the PEG ratio and PE ratio of PTGX?

    The latest valuation data shows Protagonist therapeutics, inc. (PTGX) has a Price-To-Earnings (PE) ratio of -42.7 and a Price/Earnings-To-Growth (PEG) ratio of -2.77. A PEG below 1 usually suggests the market is underestimating growth potential, while a PEG above 1 indicates high growth expectations are already priced in. Investors should conduct a comprehensive valuation by considering historical growth, market forecasts, and industry cycles.