The latest data point for Pfizer's (PFE) diluted EPS in Q1'26 shows a value of 0.47 USD, marking a modest positive figure following a negative Q4'25 result of -0.29 USD. This represents a slight year-over-year decline of approximately -9.6% in EPS growth, indicating ongoing challenges in maintaining profitability momentum into early 2026. Over the period from Q2'23 to Q1'26, PFE's diluted EPS exhibited high volatility, starting with a positive 0.41 USD in Q2'23 before plunging into negative territory with -0.42 USD in Q3'23 and a low of -0.59 USD in Q4'23, then recovering to peaks of 0.78 USD in Q3'24 and stabilizing around 0.50-0.62 USD through Q3'25. Year-over-year EPS growth was predominantly negative, with sharp declines exceeding -75% in early quarters and a notable outlier of +285.7% in Q3'24, but recent periods show erratic patterns including a +50% surge in Q2'25 followed by a steep -514% drop in Q4'25, underscoring inconsistent earnings performance likely influenced by pharmaceutical market dynamics and one-time factors.