As of Q4'25, ISRG's P/E Ratio stands at 63.22, marking a decrease from the previous quarter's value of 68.02. This latest data point reflects a continued downward movement in the latter half of 2025. Over the period from Q1'23 to Q4'25, ISRG's P/E Ratio has exhibited notable volatility, with significant peaks in Q2'24 (77.23), Q3'24 (82.75), and reaching a high of 87.82 in Q4'24. However, following this peak, the ratio has trended downward across 2025, indicating a potential shift in market sentiment or earnings growth relative to price. Overall, the chart suggests a fluctuating but recently declining valuation multiple over the observed time frame.